Report on Rotenone
نویسندگان
چکیده
منابع مشابه
Pramipexole protective effect on rotenone induced neurotoxicity in mice
Introduction: Pramipexole is a new dopaminergic drug which has been approved for PD treatment. However, we tried to find new capacity for this drug rather than symptomatic effect. Materials and Methods: A chronic rotenone model with daily oral dose of 30mg/kg was induced in mice. Pramipexole was tried in a new approach where the treatment began in the middle of rotenone course with oral dose 1m...
متن کاملThe effect of rotenone on respiration in pea cotyledon mitochondria.
Respiration utilizing NAD-linked substrates in mitochondria isolated from cotyledons of etiolated peas (Pisum sativum L. var. Homesteader) by sucrose density gradient centrifugation exhibited resistance to rotenone. The inhibited rate of alpha-ketoglutarate oxidation was equivalent to the recovered rate of malate oxidation. (The recovered rate is the rate following the transient inhibition by r...
متن کاملRotenone, Paraquat, and Parkinson’s Disease
BACKGROUND Mitochondrial dysfunction and oxidative stress are pathophysiologic mechanisms implicated in experimental models and genetic forms of Parkinson's disease (PD). Certain pesticides may affect these mechanisms, but no pesticide has been definitively associated with PD in humans. OBJECTIVES Our goal was to determine whether pesticides that cause mitochondrial dysfunction or oxidative s...
متن کاملFatality after deliberate ingestion of the pesticide rotenone: a case report
Rotenone is a pesticide derived from the roots of plants from the Leguminosae family. Poisoning following deliberate ingestion of these plant roots has commonly been reported in Papua New Guinea. However, poisoning with commercially available rotenone in humans has been reported only once previously following accidental ingestion in a 3.5-year-old child. Therefore, the optimal management of rot...
متن کاملRotenone . A Brief Review of its Chemistry , Environmental Fate , and the Toxicity of Rotenone Formulations
Background on the Chemistry of Rotenone. Rotenone is a natural product isolated from certain subtropical and tropical members of the pea family found in South America and Southeast Asia. The use of rotenone by man may be ancient, as early explorers noted Peruvian natives using crude extracts of the Cubé plant to stun fish for eating. In the early 1900’s, botanists exploring Peruvian jungles sea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 1958
ISSN: 0095-9111
DOI: 10.1093/jaoac/41.3.515a